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| FLUOXETINE HYDROCHLORIDE | |||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 54910-89-3;
52341-67-0; 57226-07-0
(Base) 56296-78-7; 59333-67-4 (HCl) |
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| EINECS NO. | 260-101-2 | ||
| FORMULA | C17H18F3NO·HCl | ||
| MOL WT. | 345.79 | ||
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | Prozac; | ||
| (±)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy] propylamine; 3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine hydrochloride; | |||
| PRICE | U$120/kg (25kgs) | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white solid | ||
| MELTING POINT | 156 - 158 C | ||
| BOILING POINT |
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| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER | |||
| pH | |||
| VAPOR DENSITY |
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REFRACTIVE INDEX |
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NFPA RATINGS |
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AUTOIGNITION |
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FLASH POINT |
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| STABILITY | Stable under normal conditions | ||
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GENERAL DESCRIPTION & APPLICATIONS |
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Fluoxetine
is a drug of Selective
Serotonin Reuptake Inhibitor (SSRI) which interferes
with serotonin ((chemically 5-hydroxytryptamine, 5-HT) transport, used to treat
depression, anxiety, obsessive-compulsive disorders (OCD), eating disorders, and
social phobias. Examples of SSRI include Fluoxetine (Prozac, Fontex),
Paroxetine (Paxil, Seroxat), Sertraline (Zoloft), Escitalopram Oxalate
(Lexapro), Citalopram (Celexa), Fluvoxamine Maleate (Luvox), Bupropion
(Wellbutrin). SSRIs have been increasingly replacing cyclic antidepressants
which have been the most common antidepressants due to less side effects and to
minimize suicide attempt. Examples of tricyclic antidepressants include
Amitriptyline (Elavil,Endep), Clomipramine (Anafranil), Desipramine (Norpramin,
Pertofrane), Doxepin (Adapin, Sinequan), Imipramine (Tofranil), Nortryptyline
(Pamelor), Protriptyline (Vivactil), Trimipramine (Surmontil) and tetracyclic
antidepressant is Maprotiline (Ludiomil). |
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| SALES SPECIFICATION | |||
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BP/USP/CP |
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IDENTIFICATION |
pass |
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ASSAY |
98.5 - 101.0% |
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LOSS ON DRYING |
1.0% max |
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RESIDUE ON IGNITION |
0.5% max |
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VOLATILE IMPURITY |
pass |
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HEAVY METALS |
20ppm max |
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| TRANSPORTATION | |||
| PACKING | | ||
| HAZARD CLASS | |||
| UN NO. | |||
| OTHER INFORMATION | |||
| Hazard Symbols: XI, Risk Phrases: 20/21/22, Safety Phrases: 36 | |||
| PRICES | |||
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